Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC

Abstract Background Clinical imaging in suspected invasive fungal disease (IFD) has a significant role early detection of and helps direct further testing treatment. Revised definitions IFD from the EORTC/MSGERC were recently published provide clarity on for definition IFD. Here, we evidence to support these revised diagnostic guidelines. Methods We reviewed data modalities techniques used characterize IFDs. Results Volumetric high-resolution computed tomography (CT) is method choice lung imaging. Although no CT radiologic pattern pathognomonic IFD, halo sign, appropriate clinical setting, highly suggestive pulmonary aspergillosis (IPA) associated with specific stages disease. The ACS not occurs later infection. By contrast, reversed sign hypodense are typical mucormycosis but occur less frequently. In noncancer populations, both “atypical” nonnodular presentations, including consolidation ground-glass opacities. Conclusions A uniform could improve quality studies aid differentiating other pathology practice. Radiologic assessment an important component work-up management Periodic review that findings patients will inform future